Hmmm, we have the bedhead against a solid wall, window down one side, and wardrobe+main doors along the other side, but the ensuie door is at the foot of the bed.
I find I sleep better in this place (exactly north-south - head towards north) than at our old one (east-west - head towards east).
(but then maybe that's because we don't have the 3am fart-can exhausts & doof-doof-doof crap beside us anymore.)